KMID : 0828520100140030171
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Journal of the Korean Geriatrics Society 2010 Volume.14 No. 3 p.171 ~ p.174
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A Case of Dopamine Dysregulation Syndrome and Repetitive Behavior Caused by Levodopa in Parkinson¡¯s Disease
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Huh Jung-Won
Kim Min-Jeong
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Abstract
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Levodopa treatment in Parkinson¡¯s disease (PD) can cause a wide range of non-motor manifestations including poor impulse control and stereotyped behaviors. Punding is a term used to describe complex prolonged, purposeless and repetitive behavior in patients under dopamine replacement therapy. We report a 64-year-old PD patient who, concomitantly with self-increment of levodopa, developed punding behaviors in association with dopamine dysregulation syndrome. Gradual reduction of dopaminergic medication partially alleviated repetitive behavior over time.
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KEYWORD
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Parkinson disease, Dopamine dysregulation syndrome, Levodopa
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